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Because AOD-9604 works peripherally on fat tissue through beta-3 adrenergic receptors without affecting central appetite pathways, there is no adaptation of hunger-regulating systems and therefore no rebound effect when stopping
Parameters include glycated hemoglobin (HbA1c), fasting plasma glucose, body mass index (BMI), estimated glomerular filtration rate (eGFR), triglycerides, LDL cholesterol, and alanine aminotransferase (ALT)
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