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We observed robust inhibition of p70S6K levels in GPX4 knockdown cells compared to non-targeted cells (Fig

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32, 44 We further extend these findings by examining a larger sample of carefully selected tissues for multiple markers of oxidative protein/DNA damage (3-NT, 8-oxo-dG), as well as functional biomarkers of inflammation (3-CT) and mitochondrial superoxide production (aconitase activity)

The microenvironments in the follicular fluid, the fallopian tubes, and the abdominal cavity are particularly important for optimal fertility

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