[2] [3] However, when a gallstone obstructs the bile duct and causes acute cholestasis, a reflexive smooth muscle spasm often occurs, resulting in an intense cramp-like visceral pain in the right upper part of the abdomen known as a biliary colic (or "gallbladder attack")
Additionally, glutathione facilitates the conversion from darker eumelanin to lighter pheomelanin through cysteine conjugation with dopaquinone
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doi:10.1016/j.bbagen.2012.10.012 Richie JP Jr, Nichenametla S, Neidig W, et al
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