2.41% of people taking DPP-4 inhibitors developed epilepsy
When administered, Ozempic stimulates insulin release, decreases glucagon levels, and slows down gastric emptying, leading to increased satiety, reduced hunger, lower calorie intake, and eventually, weight loss
However, in a recent study on the inhibition of Hepa1-6 cell proliferation induced by oxidative stress, we found that increased expression of GPX6 protein may play a role in inhibiting oxidative stress (Usategui-Martn et al., 2022)
The post-meal increases in insulin production from Ozempic or Mounjaro are healthier than the constantly high insulin levels that result from insulin resistance
However, whether glucagon-like peptide-1 (GLP-1) mediated the protective effect of DPP-4 inhibition (DPP-4i) on PH is unclear