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Foot Ankle Clin
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While B12 is generally safe, caution is needed in specific clinical situations: Lebers Disease (Hereditary Optic Neuropathy): B12 injections are generally contraindicated or should be used with extreme caution, as they may potentially aggravate optic atrophy in this rare condition
The recommendation: remove the vial from refrigeration 15-20 minutes before drawing the dose, or warm the filled syringe in your palm for 60 seconds before injecting
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