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In patients with non-alcoholic steatohepatitis (NASH), there is marked downregulation of mtDNA-encoded polypeptides and attenuation of the respiratory chain complex
Besides, given its role as an antioxidant in the human body, riboflavin may act as a protective agent against neurological disorders, such as Parkinsons Disease (DP), which has oxidative stress as a contributing factor in DP development (47)
The samples were centrifuged, and the supernatant was subjected to a GSH assay based on a kinetic enzymatic recycling method that detects the oxidation of GSH by 5,5-dithiobis-2-nitrobenzoic acid (DTNB) and glutathione reductase to measure the GSH content in cells 74
2023;120: e2204750120
Oxidative stress is increased in cases of liver disease owing to the effects of inflammation, reduced blood flow and mitochondrial damage by toxins, drugs or bile acids
