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The most commonly reported adverse effects in clinical trials are gastrointestinal in nature, particularly during dose escalation
Akt-dependent proapoptotic effects of dietary restriction on late-stage management of a phosphatase and tensin homologue/tuberous sclerosis complex 2-deficient mouse astrocytoma
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Interestingly, monocyte differentiation into M1- M (mimicking the recruitment of monocytes to the site on infection) was inhibited by the presence of HBV as shown by a strong decrease of IL-1 and IL-6 secretion
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