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Were doing things with these drugs that dont mimic the biology, said Seeley
Do you have a team to turn to with questions or when you hit a plateau
General skincare measures can help support skin barrier function and reduce sensitivity: Moisturise regularly using fragrance-free, hypoallergenic emollients to maintain skin hydration, particularly if dryness accompanies weight loss Avoid harsh skincare products containing alcohol, strong fragrances, or exfoliating acids, which may exacerbate sensitivity Use broad-spectrum SPF 30+ sunscreen daily as a general skin protection measure, and limit prolonged sun exposure Wear loose, breathable clothing to minimise friction against sensitive skin areas Apply a cool compress to injection site reactions to help reduce localised redness or discomfort Maintain a balanced diet in line with the NHS Eatwell Guide
A later animal study had similar results, linking severe B12 deficiency to increased body fat
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