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Third, given the relatively recent introduction of GLP-1 RAs as antidiabetic treatments, the median follow-up duration in this study may have been too brief to adequately assess the long-term risk of cancer development
doi:10.1016/j.bbcan.2014.04.004
J Appl Lab Med
GLP-1 medicines are started low and stepped up deliberately: for Wegovy, 0.25 mg for weeks 1 to 4, then 0.5 mg, 1 mg, 1.7 mg, reaching the 2.4 mg maintenance dose at week 16
TDP-43 Q331K C57BL/6 N transgenic mice were obtained from the Jackson Laboratory, stock number 01793 and were originally generated in the Cleveland lab 24 and extensively characterised in-house 25
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