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However, mutation of genes involved in the expression of GSK3 and exaggerated signaling provokes the development and progression of AD by inducing the production and the accumulation of A and tau protein (Chauhan et al

Dose escalation should be clinically guided

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The glucagon-like peptide-1 receptor (GLP-1R), a clinically relevant class B1 GPCR, stimulates production of the second messenger cyclic adenosine monophosphate (cAMP) upon activation by the native hormone, GLP-1