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On the data side, the Lau phase 2 obesity trial showed Cagrilintide monotherapy producing dose-related weight loss, reaching close to 10.8 percent at the top dose over roughly 26 weeks, against about 3 percent on placebo
This overlap makes baseline IBD control essential before starting GLP-1 therapy and close monitoring during titration critical for distinguishing medication effects from disease activity
Journal Neurological Sciences
Always consult your GP or pharmacist before starting any laxative regimen, particularly if you have inflammatory bowel disease, intestinal obstruction, severe abdominal pain, or are pregnant or breastfeeding
This dual effect on both sides of the energy balance equation is why retatrutide produced the highest weight loss percentages of any single-agent trial
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