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For patients planning a series of treatments, clinics usually follow up to track progress and adjust schedules as needed

Oxidative stress occurs when there is an imbalance between free radicalsunstable molecules that can damage cellsand the antioxidants meant to neutralise them

Furthermore, FOXO4-DRI targets the tumor suppressor p53, a crucial protein, which may lead to various side effects in clinical trials 37

To understand the non-monotone behavior of GSH, it is crucial to consider that there are two incoming fluxes to GSH, GS and GR, and two outgoing fluxes, GPX and a large flux out into the blood [Figure 2B]

A portion of the iron in the cytoplasm is transported to the mitochondria for the synthesis of heme and iron-sulfur clusters (ISCs) [72]