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This warning was grounded on a wide number of studies reviewed in (Micallef et al., 2020b) including a recent report of the French Pharmacovigilance Network conducted in 2019 (Crpv De Tours, CRPV de Marseille, 2019) showing that the use of NSAIDs (even if given for short times and/or associated to antibiotics) for the treatment of fever and non-rheumatic pain (which may be indicative of an underlying infection) increases the risk of severe bacterial complications, particularly of the lungs, and on the supposed ibuprofen-induced A angiotensin-converting enzyme 2 (ACE2) overexpression

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As indicated above, the steroid hormone action of vitamin D occurs via the action of calcitriol binding to a specific intracellular receptor that is a member of the nuclear receptor family of hormone receptors called the vitamin D receptor (VDR)

those in the most deprived communities, who are also at higher risk of obesity, are missing out