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Some limitations of this study should be acknowledged

Semaglutide causes nausea in a significant percentage of users, particularly during the dose-escalation phase

Postsynaptic spike firing reduces synaptic GABAA responses in hippocampal pyramidal cells

This contraindication reflects the theoretical concern that GLP-1 receptor stimulation could promote recurrence or progression of residual C-cell disease, even though human C-cells express minimal GLP-1 receptors

This includes glutathione