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A bivalent cyclic RGD-siRNA conjugate enhances the antitumor effect of apatinib via co-inhibiting VEGFR2 in non-small cell lung cancer xenografts

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After 72 weeks of Mounjaro treatment, study participants lost 16% (5 mg/week), 21.4% (10 mg/week), and 22.5% (15 mg/week) of their starting body weight