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These are not published trials
ODS, Office of Dietary Supplements, National Institutes of Health
Vitamins C, E, and A also provide protection through various mechanisms, including direct scavenging of free radicals and modulation of cellular pathways
Notably, in vitro experiments revealed that inhibition of either PI3K or AKT negated the beneficial effects of berberine on IR, underscoring the pivotal role of the PI3K/AKT pathway in its mechanism of action (Yu et al., 2021)
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