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Some usage-limiting properties of the designed peptides, including low selectivity and tumor cell uptake, poor tumor permeability and passing through the BBB in glioma cancer, and low plasma stability, can be improved by several techniques, such as intracellular delivery via the intracellular pathway, ligand-mediated tumor targeting, and nanoparticle-based drug delivery systems

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Naturally Occurring Peptides Naturally occurring peptides are derived from biological sources, such as animal or plant proteins

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S2) UniFrac analyses and BrayCurtis dissimilarity analysis (Supplementary Fig