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Next we move on to skincare

These findings indicate that while some individuals may observe changes within weeks, the effects are typically minimal and temporary

Albiglutide, dulaglutide, exenatide, liraglutide, lixisenatide, orforglipron and semaglutide used in the clinic are monoGLP-1RAs, tirzepatide acts not only on GLP1R, but also on glucose-dependent receptors of insulinotropic peptide (GIP), and retatrutide is a triple agonist of GLP-1, GIP and glucagon receptors

Furthermore, this improvement was not permanent and, after six months of administration, only one (6.2%) participant continued to experience skin tone reduction

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