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Anyone experiencing persistent or unexpected symptoms should discontinue use and seek medical advice promptly

Reasoning: The reclassification was approved to allow pharmacists to supply the product without a prescription for the initial treatment of stable, mild-to-moderate plaque psoriasis in adults, increasing self-care options

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In people with obesity and established cardiovascular disease but without diabetes, semaglutide 2.4 mg resulted in 20% reduction in major adverse cardiovascular events [(MACE), death from cardiovascular causes, nonfatal myocardial infarction or nonfatal stroke] compared to placebo (SELECT trial) after a mean follow-up of 39.8 months this is the first trial demonstrating cardiovascular benefit for an obesity pharmacotherapy [110]