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Adipocyte energy expenditure published animal models have explored NNMT inhibition with 5-Amino-1MQ in diet-induced-obesity rodents, examining adipose-tissue mass, energy expenditure, and metabolic markers
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Open Biol 10:200223 Wu Y, Zhang K, Liu R, Zhang H, Chen D, Yu S, Chen W, Wan S, Zhang Y, Jia Z (2020) MicroRNA-21-3p accelerates diabetic wound healing in mice by downregulating SPRY1
NMR relaxation experiments for the recombinant L -version of the FOXO4-DRI sequence were recorded using 13 C, 15 N-labeled samples at 300 M in a buffer containing 50 mM NaH 2 PO 4 /Na 2 HPO 4 , pH 6.5, 0.04 % NaN 3 , 2.5 mM DTT and 10 % D 2 O in the absence and in presence of 400 M synthetic D -p53 TAD2 peptide using the same NMR parameters
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