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This clinical study shows that oral GSH has lower bioavailability due to breakdown in the gut, compromising blood levels and antioxidant support

10.1016/j.chembiol.2008.02.010 Chem

Structure [edit] The glutathione binding site, or "G-site", is located in the thioredoxin-like domain of both cytosolic and mitochondrial GSTs

So as soon as somebody is thinking about a weight loss program and especially is considering the use of any weight loss medication, especially including and especially GLP-1 receptor agonists, for me I think the key thing is to get strength training ticked off, make sure thats a regular occurrence in that persons lifestyle so that theyre either building or retaining as much muscle as they can