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In a phase 3 clinical trial called SURMOUNT-2, 938 obese or overweight adults with type-2 diabetes were assigned to one of three groups: a placebo, 10 mg of Mounjaro/Zepbound, or 15 mg of Mounjaro/Zepbound
Niacin Niacin (nicotinic acid) is also known as vitamin B3
About the Compounds BPC-157 a synthetic 15-amino-acid peptide (pentadecapeptide) derived from a protein found in human gastric juice
Cytokine quantification Cytokine concentrations in culture supernatants and BALF samples were quantified using either LEGENDplex Mouse Th Panel or LEGENDplex Human Th2 Panel (BioLegend) per the manufacturers instructions and described previously (47, 71, 73, 75, 76)
Metabolic dysregulation, such as disorders in lipid metabolism, glucose metabolism abnormalities, and issues with amino acid metabolism, exacerbates pancreatic injury and inflammatory responses
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