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Arginine is an essential amino acid that may help improve blood flow through the heart, help regulate blood pressure and manage mitochondrial stress, and help the heart work more efficiently
Critically, this redox adaptation is a key mechanism of resistance to radiotherapy and many chemotherapeutic agents, such as cisplatin and doxorubicin, which depend on generating oxidative damage to exert their cytotoxic effects [33]
This mechanism has made it a subject of significant research interest in dermatology and skin pigmentation studies
Darmaun D, Smith SD, Sweeten S, Sager BK, Welch S, Mauras N
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