The micronutrient Mg 2+ also has been proposed as a treatment for NIHL, not only for its function as a potential cochlear vasodilator but for other pharmacological properties, which include modulation of NMDA glutamate receptors and the regulation of calcium influx into hair cells, preventing or reducing apoptosis (Cevette et al., 2003
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South African Medical Journal , 106(8):782-786
In controlled physiological concentrations, ROS perform the role of essential signaling molecules that modulate various biological processes like cell proliferation, immune response, and apoptosis [26]