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Bi-continuous term refers to two distinct hydrophilic zones separated by the bilayer [29]

The TB-500 weekly band rests on two veterinary anchors that disagree by 2.6x an equine protocol scaling to 2.29 mg/week for a 70 kg human, and back-calculation from a 5 mg greyhound dose giving 5.91 mg/week

It has Phase 3 REDEFINE-1 data showing about 22.7% weight loss at 68 weeks, and an NDA was filed with FDA in December 2025

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Store at controlled room temperature 15C 30C (59F 86F)