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Luckily, our bodies come equip to handle some of this oxidative stress through creating anti-oxidants (like glutathione) to keep the cascade of damage in check
One of the primary drivers of ferroptosis, lipid peroxidation, further stimulates TGF-/Smad signaling and exacerbates fibrosis progression
Jan 2013;78(1):7-17
Funding This work was supported by grants U24CA270823, U24CA271079, U24CA271012, U24CA271075, U24CA271076, U24CA271037, U24CA271114, U01CA271412, U01CA271410, U01CA271407, U01CA271402 and U24CA210955 from the National Cancer Institutes CPTAC
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