examples of glp 1 inhibitors GLP-1-based therapies: current knowledge differences between native GLP-1 Agonists: Using Semaglutide, Tirzepatide,

GLP-1 receptor agonists mimic the action of naturally occurring hormones that regulate blood glucose and appetite by: Slowing gastric emptying, promoting feelings of fullness Reducing appetite signals in the brains hunger centers Improving insulin secretion while suppressing glucagon release Creating a caloric deficit through reduced food intake Originally developed for type 2 diabetes management, these medications have gained FDA approval for chronic weight management in adults with obesity or overweight with weight-related comorbidities

Velnex Medicare Bactolac Pharmaceutical, Inc

Syed Kashif Hussain Kazmi Endocrinologist | England #Endocrinology #DiabetesCare #ObesityManagement #GLP1 #Tirzepatide #Semaglutide #NHS #EvidenceBasedMedicine #MedEd #CardiometabolicHealth Thank you Kashif

national Medicare cohort study, also included 21,402 pairs of patients treated with a GLP-1 RA versus DPP-4 inhibitors and found no differences in suicidal ideation and behaviors between groups [29]

The approval was granted based on demonstrated improvements in MASH and fibrosis, and a confirmatory study is currently underway