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This is the second signal Mounjaro and Zepbound work on.[7] Glucagon

The proportion of obese patients (BMI 30 kg/m 2 ) fell from 71.0% to 43.3% in the semaglutide group versus 71.9% to 67.9% in the placebo group

Safety assessments were conducted from baseline through end-of-study follow-up, and pharmacokinetic and exploratory assessments were performed at prespecified time points, including serial sampling up to 672 h after the final dose

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Contact your GP or prescribing clinician promptly, as sudden appetite changes may indicate treatment tolerance, missed doses, or an underlying medical condition requiring assessment