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You'll see articles that say "10-14% of patients get headaches on semaglutide" without distinguishing between: Positional headaches from CSF dynamics (this article's focus) Tension headaches from medication-induced stress or sleep disruption Migraine triggered or worsened by the medication Nausea-associated headaches (part of the GI symptom cluster) Dehydration headaches without a positional component Medication overuse headaches from treating the above These are mechanistically distinct
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