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Jornayvaz FR, Shulman GI

Results demonstrated that AOD-9604 displayed a very good safety and tolerability profile indistinguishable from placebo. Critically, the peptide produced no clinically significant alterations in IGF-1 levels, no glucose intolerance or insulin resistance, and no anti-AOD9604 antibodies in any participant

Metformin is commonly used as a first-line treatment along with diet and exercise for those just diagnosed with type 2 diabetes

The fundamentals of peptides article provides broader context for understanding where these compounds fit in the regulatory framework

Apart from Type 2 diabetes, Jardiance is also approved to reduce health risks linked to heart and kidney disease