This article was inspired by a question from a health-conscious client who follows a heart-healthy lifestyle that includes strength training, interval workouts, infrared sauna sessions, and light supplementation with nitric oxide and glutathione
It also plays a vital role in the body's natural detoxification pathways and helps "recycle" other antioxidants like Vitamin C and Vitamin E
The antioxidant mechanisms of polyphenols primarily involve neutralizing free radicals by electron and/or hydrogen atom transfer, reducing metal-dependent hydroxyl radicals via chelation mechanisms, mitigating mitochondrial dysfunction to reduce cell apoptosis, and enhancing the endogenous antioxidant enzyme defense system by activating nuclear factor E2-related factor 2 (NRF2), among other pathways [67, 68]
When you take Glutathione orally, much of it is broken down by your digestive system before it can be absorbed
As an antioxidant, glutathione also supports overall skin health, making it a popular oral supplement for gradual, visible skin improvement