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Ensure proper education on any differences in administration methods, and consider scheduling brief follow-up appointments to verify patients understand how to use new delivery methods correctly

Week 46 Check Dose Escalation Phase Semaglutide begins at a low dose and is escalated over weeks

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Patients with a history of pancreatitis, medullary thyroid cancer, or multiple endocrine neoplasia type 2 should avoid semaglutide regardless of Lipo C use, as semaglutide carries a black-box warning for these conditions