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Generation 1: semaglutide, GLP-1 monoagonist Semaglutide activates only the GLP-1 receptor
The cyclic structure is maintained by the disulfide bond, which is susceptible to oxidative cleavage in the presence of dissolved oxygen, light exposure, and temperatures above 8C
According to the Cleveland Clinic, these drugs are used not only for diabetes but also for obesity, with additional potential benefits for cardiovascular health and lipid profiles
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National Academy of Sciences National Research Council 223244
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