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LC-MS can detect several impurity types including truncated peptides, oxidation products, deamidated forms, sequence variants, and D-amino acid isomers
This approach requires a provider who is experienced with compounding calculations and should never be attempted without professional guidance
Pathological -syn aggregates exhibit dual neurotoxic effects: Synaptic transmission impairment (123) and autophagic-lysosomal system dysfunction that promotes cytotoxic substrate accumulation (124)
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