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A 2023 study of more than 17,000 patients published in the New England Journal of Medicine found that semaglutide reduced the risk of major cardiovascular events including heart attack, stroke and cardiovascular death by about 20% in overweight or obese adults who already have cardiovascular disease but not diabetes

Clinical guidance for intramuscular injections points to a 22 to 25 gauge needle, given at a 90-degree angle, with the length chosen so it reaches muscle without going too deep

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Supplementary information Supplementary Method (download DOC Method for fixing tissues and cultured cells for immunogold immunohistochemistry