Very important and practically oriented paper Nice overview of advantages and limitations A must read for anybody who treats these patients To view or add a comment, sign in GLP-1RAs Show Significant Liver and Metabolic Benefits in MASLD A new systematic review and meta-analysis of 32 randomized controlled trials reveals that GLP-1 receptor agonists (GLP-1RAs) significantly improve liver and metabolic outcomes in patients with Metabolic dysfunction-Associated Steatotic Liver Disease (MASLD), far outperforming DPP-4 inhibitors, which showed minimal effects beyond glycemic control
A generic version of liraglutide received FDA approval recently and is available for as low as $221 per month with discount coupons, making it the cheapest FDA-approved brand-name GLP-1 injection on the market
The increased expression of Ranbp2, Lmna, Ipo5, and Lrrc59, which play positive roles in regulating protein import into the nucleus, suggested that oxidative stress triggered nuclear-cytoplasmic transport participating in DNA/chromosome repair in IVF-derived embryos 24,25
Until that point, retatrutide remains an investigational drug
Combining AHK-Cu with other evidence-based approaches often produces better results than any single intervention alone