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After reconstituting with 3.0 mL of water, 1 unit on a U-100 insulin syringe will be equivalent to about 33.3 mcg of the total blend

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[4] Patients with benzyl alcohol allergy should not be exposed to this diluent

It is real for a subset of users, and regulators have responded: the FDA added persistent sexual dysfunction to the label and, in 2022, agreed to list suicidal ideation as an adverse reaction

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