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The FDA resolved the semaglutide shortage in late 2024 and the tirzepatide shortage in early 2025, which narrowed but did not eliminate legitimate compounding activity
In addition to helping reduce calorie intake, its activation of glucagon receptors may increase how efficiently the body burns stored fat, rather than relying on appetite suppression alone
It holds no MHRA or EMA marketing authorisation
There were no statistically significant differences observed between the two subgroups ( P = 0.06) (Additional file 2: Fig
Regular review of injection sites by a clinician or diabetes specialist nurse is recommended for anyone on long-term injectable therapy
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