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Nave T cells rely primarily on oxidative phosphorylation to generate ATP, whereas activated T cells shift their metabolism toward aerobic glycolysis (Warburg effect) to meet the demands of growth, proliferation, and effector functions, such as IFN- production (136)

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Research applications In vitro, investigators use GHK-Cu as a model copper-peptide when examining copper transport and coordination chemistry, and when probing interactions with extracellular-matrix (ECM) components

Risk Note: For example, Infusion studies in fetal sheep models found that high doses of IGF-1 LR3 were found to induced severe hypoglycemia and hypoxemia