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It limits the formation of new fat cells

however, a higher proportion of total AEs was classed as mild in severity compared with the overall population

It is not licensed by the MHRA, is not available on NHS prescription, and has not been appraised by NICE for any indication

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Local application of GLP-1 to the core of the NAc increases the number of neurons expressing the immediate early gene, c-fos, in this region (Dossat et al., Mesolimbic GLP-1R driven food-oriented behaviors Even though the research on the physiological role of the mesolimbic GLP-1 activation is in its early stages the first studies addressing this question provide compelling evidence for an important role of the GLP-1 system in the mesolimbic circuitry and resulting reduction in food intake