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In another double-blind, placebo-controlled trial, an improvement in cognitive performance (i.e., MMSE score) was reported in AD patients randomized to receive 800 IU/day of all - rac --tocopherol (360 mg/day of RRR --tocopherol) for six months only when the treatment effectively reduced oxidative stress (as assessed by the measure of total glutathione and markers of lipid peroxidation in the blood) (110)

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doi: 10.1128/iai.61.10.4392-4397.1993 41 EcheniqueJ.KadiogluA.RomaoS.AndrewP

doi: 10.1055/s-0042-110491 30 WertenbruchTWillenbergHSSagertCNguyenTBBahloMFeldkampJet al

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