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In a study, participants on Semaglutide lost an average of 5.9% of their body weight after 3 months and 10.9% at 6 months
The primary outcomes were the percentage weight change and the proportion of participants losing at least 5% of their baseline weight, using treatment-policy estimand analysis (intention-to-treat principle)
Retatrutide showed a 7.2% weight loss at the lowest dose over 24 weeks
NICE and the BNF provide clear guidance on appropriate use, emphasising that injections should be reserved for cases where oral supplementation is inadequate or inappropriate
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