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Agrati C, Sacchi A, Bordoni V, Cimini E, Notari S, Grassi G, et al
Most providers recommend that there should be at least 48 hours between any two doses of a GLP-1 medication
The result at week 88: Continued tirzepatide: :Lost an additional 5.5% of body weight (total loss from baseline: ~25%) Switched to placebo: Regained 14.0% of body weight (net loss from baseline: ~9%) A 19-point swing between continued and discontinued groups
This further adds to phosphorylation of downstream targets involved in transcriptional regulation
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