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378 Certain scholars posit that the removal of benzbromarone from the market may not align with the best interests of patients with gout, with the argument that conceivable toxicity could be mitigated through a cautious approach involving gradual dosage escalation coupled with vigilant monitoring of liver function

Grapefruit is one commonly cited concern due to its CYP3A4 enzyme inhibition, which can alter drug metabolism in the liver

This may point again to tissue fragility in people with clEDS

If there are factors that are making it difficult for you to take your medication as prescribed, they may be able to help you troubleshoot and find a regimen that works better for you

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