In this randomized trial of more than 9300 subjects with T2DM and high cardiovascular risk, liraglutide was seen to decrease the incidence of the composite cardiovascular primary endpoint (occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke) compared with placebo (13.0 and 14.9% in the liraglutide and placebo group, respectively
And if youve got multiple pens or vials on hand, its a good idea to rotate them so youre always using the ones closest to their expiration date first
Sigalet DL, Bawazir O, Martin GR, Wallace LE, Zaharko G, Miller A, et al
This is when the wearing-off effect is strongest, when hunger fluctuations are most noticeable, and when the temptation to dose more frequently feels most compelling
In addition, dont underestimate the importance of protein for satiety, maintaining and building muscle mass, and promoting a healthy weight.