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Research using MT-1 in cell systems expressing these variants documents reduced melanogenesis, impaired MITF activation, and diminished DNA repair responses
It can improve skin clarity and even reduce hyperpigmentation
The proposed mechanism suggests that this effect occurs through the downregulation of the CREB pathway, thereby inhibiting melanin synthesis (Yoon et al., 2023)
However, because both retinol and glutathione can be active ingredients, combining them can lead to irritation, especially for sensitive skin types
This area is yet to be explored in head and neck cancer progression to find suitable targets against head and neck cancer progression
