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Peptides are involved in almost every bodily action

And the peptides ability to attract stem cells and stimulate fibroblast proliferation provides the cellular workforce needed for tissue reconstruction

PLoS One 10 , e0127075 (2015)

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In addition, combined investigations using human HSCR samples and endothelin receptor B-deficient mice have demonstrated impaired epithelial regeneration and disrupted stromal-epithelial signaling, characterized by depletion of LGR5 stem cells and a shift toward proinflammatory stromal populations, which may contribute to Hirschsprung-associated enterocolitis 136