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1 Conclusion: In the current trial, treatment with tirzepatide, a dual GIP and GLP-1 receptor agonist was superior to semaglutide, a selective GLP-1 receptor agonist, in respect to reduction in body weight and waist circumference 1,*,, The safety profile of Trizepatide in this trial was consistent with the safety data reported in previous SURMOUNT trials 1,* THERAPEUTIC INDICATION 1 : Type 2 diabetes mellitus MOUNJARO is indicated for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise as monotherapy when metformin is considered inappropriate due to intolerance or contraindications in addition to other medicinal products for the treatment of diabetes
Cost of Oral vs Injectable and Other Therapies No new drug adoption is possible without the proper cost-related analysis in relation to already available options
The practice of doubling the infusion rate is increasingly accepted, but tripling or quadrupling the dose remains more controversial
In April 2025, Noom sponsored a back cover advertisement in the The Wall Street Journal calling for the creation of a High-Priced Drug List by HHS
5j, p = 0.0025)
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