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Long-term safety data spanning 6-month treatment periods show no significant adverse events or laboratory abnormalities, making KPV suitable for extended therapeutic protocols

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doi: 10.1111/j.1478-3231.2010.02261.x 9 FattovichGStroffoliniTZagniIDonatoF

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Data were low-pass filtered at 2 kHz and a 5-ms template (2 ms baseline, 2 pA amplitude, 0.5 ms rise time, and 1 ms decay time) was used to detect spontaneous EPSCs