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Since lactate production acidifies the environment, physiologic lactate concentrations are kept in a narrow range (1.5-3 mM) in blood and tissues of healthy individuals
After a 30-min stabilization incubation, PBS (without IBMX) and 100 M 3-isobutyl-1-methylxanthine (with IBMX) (Sigma Chemicals, St Louis Mo) was added and incubated for 60 min so that each rat served as its own control
JAMA 2008;300:2253-62
Saliva does all kinds of things
A five-year, randomized, double-blind, placebo-controlled trial in healthy Danish older people (ages at inclusion, 60-74 years) found that selenium supplementation (100-300 g/day) had little-to-no impact on circulating levels of antioxidant enzymes, including GPx (166)
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